Aeromonas salmonicida of Contribution of Type IV Pili to the Virulence
نویسندگان
چکیده
منابع مشابه
Contribution of the type III secretion system (TTSS) to virulence of Aeromonas salmonicida subsp. salmonicida.
The recently described type III secretion system (TTSS) of Aeromonas salmonicida subsp. salmonicida has been linked to virulence in salmonids. In this study, three TTSS effector genes, aexT, aopH or aopO, were inactivated by deletion, as was ascC, the gene encoding the outer-membrane pore of the secretion apparatus. Effects on virulence were assayed by live challenge of Atlantic salmon (Salmo s...
متن کاملType III secretion genes in Aeromonas salmonicida subsp salmonicida are located on a large thermolabile virulence plasmid.
Type III secretion genes in Aeromonas salmonicida subsp. salmonicida are located on a large plasmid of approximately 140 kb. Cultivation of this organism at elevated temperatures such as 25 degrees C can, however, result in loss of this plasmid. This is accompanied by a loss of virulence for cultured fish cells.
متن کاملDraft Genome Sequence of the Type Strain Aeromonas salmonicida subsp. salmonicida ATCC 33658
Here, we report the draft genome sequence of the type strain Aeromonas salmonicida subsp. salmonicida ATCC 33658 isolated from Salmo salar The size of the genome is 4,728,143 bp with a G+C content of 58.5%. The A. salmonicida subsp. salmonicida ATCC 33658 genome lacks essential virulence genes that were likely lost during genomic rearrangements.
متن کاملAeromonas salmonicida subsp. salmonicida in the light of its type-three secretion system
Aeromonas salmonicida subsp. salmonicida is an important pathogen in salmonid aquaculture and is responsible for the typical furunculosis. The type-three secretion system (T3SS) is a major virulence system. In this work, we review structure and function of this highly sophisticated nanosyringe in A. salmonicida. Based on the literature as well as personal experimental observations, we document ...
متن کاملEvidence for a type III secretion system in Aeromonas salmonicida subsp. salmonicida.
Aeromonas salmonicida subsp. salmonicida, the etiological agent of furunculosis, is an important fish pathogen. We have screened this bacterium with a broad-host-range probe directed against yscV, the gene that encodes the archetype of a highly conserved family of inner membrane proteins found in every known type III secretion system. This has led to the identification of seven open reading fra...
متن کامل